Description

1-Methylimidazole-D6 is a deuterated analog of 1-methylimidazole, a versatile heterocyclic compound and a key building block in organic synthesis. This isotopically labeled version is essential for advanced research and development, particularly in analytical chemistry and pharmaceutical studies where precise molecular tracking is required. It is primarily used by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications such as NMR spectroscopy, mass spectrometry, and as a precursor in the synthesis of labeled compounds.

Application

• NMR Spectroscopy Solvent & Internal Standard: Used as a deuterated solvent or chemical shift reference in nuclear magnetic resonance (NMR) analysis.
• Mass Spectrometry Tracer Studies: Serves as a stable isotope-labeled internal standard for accurate quantification and metabolic pathway tracing in LC-MS and GC-MS.
• Pharmaceutical Intermediate Synthesis: Acts as a key deuterated building block in the research and development of novel Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Mechanistic Reaction Studies: Employed in kinetic and mechanistic studies to investigate reaction pathways and catalysis, particularly in organometallic chemistry.
• Polymer & Material Science Research: Utilized in the synthesis of specialized polymers, ionic liquids, and advanced materials where deuterium labeling is required for structural analysis.
• Agrochemical Research: Used in the development and analysis of deuterated pesticides or herbicides to study environmental fate and metabolic processes.

Basic Information

Product Name	1-Methylimidazole-D6
CAS No.	285978-27-0
Molecular Formula	C4D6N2
Molecular Weight	88.13 g/mol
Synonyms	1-Methyl-1H-imidazole-d6; N-Methylimidazole-d6; 1-Methylimidazole (hexadeuterated); 1-Methyl-1H-imidazole-2,4,5-d3-(N-methyl-d3); 1-Methylimidazole-d6 (N-CD3, 2,4,5-D3); N-Methyl-d3-imidazole-2,4,5-d3; 1-Methylimidazole (D6, 98%); Deuterated N-Methylimidazole
EINECS	Contact for details

Quality Control

Our 1-Methylimidazole-D6 is produced under strict quality management protocols to ensure high isotopic and chemical purity, critical for sensitive analytical applications. Each batch is analyzed using advanced techniques including NMR, GC-MS, and HPLC to verify deuterium incorporation and chemical specifications. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and solvent residues is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (D)	≥ 98 atom % D
Isotopic Distribution (NMR/MS)	D6 ≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.