Description

2,6-Di(tert-Butyl-D9)-4-Methylphenol-3,5-D2 is a deuterated isotopologue of the widely used antioxidant Butylated Hydroxytoluene (BHT). This compound matters for its role as a stable, non-reactive internal standard in advanced analytical chemistry, enabling precise quantification and method validation. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and material science industries who require high-fidelity analytical standards for mass spectrometry (MS), nuclear magnetic resonance (NMR), and other spectroscopic techniques.

Application

• Internal Standard for Mass Spectrometry (MS): Provides a stable, isotopically labeled reference for the accurate quantification of BHT and related phenolic antioxidants in complex matrices.
• NMR Spectroscopy Studies: Used as a probe in mechanistic and kinetic studies due to its distinct deuterium NMR signals, helping elucidate reaction pathways.
• Pharmaceutical Analysis: Critical for developing and validating analytical methods to measure antioxidant content and degradation products in drug formulations and active pharmaceutical ingredients (APIs).
• Polymer & Material Science Research: Serves as a tracer to study the migration, efficiency, and degradation of antioxidant additives in plastics, rubbers, and fuels.
• Metabolomics & Stable Isotope Labeling: Employed in metabolic flux analysis and tracing studies within biological systems.
• Reference Material for Regulatory Testing: Supports compliance testing for industries requiring precise measurement of antioxidant levels to meet FDA, EPA, or REACH guidelines.

Basic Information

Product Name	2,6-Di(tert-Butyl-D9)-4-Methylphenol-3,5-D2
CAS No.	285978-26-9
Molecular Formula	C15D20O
Molecular Weight	228.41 g/mol
Synonyms	BHT-d20; Deuterated BHT; 2,6-Bis(tert-butyl-d9)-4-methylphenol-3,5-d2; 3,5-Dideutero-2,6-bis(trideuterio-tert-butyl)-4-methylphenol; Butylated Hydroxytoluene-d20; DBHT-d20; 2,6-Di-tert-butyl-4-methylphenol-d20; Antioxidant 264-d20
EINECS	Contact for details

Quality Control

Our deuterated analytical standards are produced under strict quality control to ensure the highest isotopic purity and chemical integrity, which is critical for their function as internal standards. Each batch is characterized using advanced techniques including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >98 atom % D), chemical purity, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.