Description

Acetic Acid-2-13C,D4 is a high-purity, isotopically labeled derivative of acetic acid, specifically enriched with carbon-13 at the C2 position and deuterium (D) at four positions. This compound is essential for advanced analytical and research applications where precise molecular tracking and quantification are required. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, metabolomics, and environmental science sectors for use as an internal standard in mass spectrometry and NMR spectroscopy.

Application

• Internal Standard for Mass Spectrometry (MS): Provides a stable, non-interfering reference peak for the accurate quantification of acetic acid and related metabolites in complex biological and chemical matrices.
• NMR Spectroscopy Studies: Serves as a crucial tracer in metabolic flux analysis and reaction mechanism studies due to its distinct 13C and 2H (D) nuclear magnetic resonance signals.
• Pharmaceutical Research & Development: Used in drug metabolism and pharmacokinetics (DMPK) studies to trace the fate of acetate moieties in novel drug candidates.
• Metabolomics and Stable Isotope Labeling: Enables precise tracking of acetate incorporation and utilization in cellular pathways, aiding in the discovery of biomarkers and disease mechanisms.
• Environmental Analysis: Acts as a labeled standard for detecting and quantifying volatile fatty acids, including acetic acid, in environmental samples.
• Chemical Synthesis Research: Employed as a labeled starting material or reagent to synthesize more complex isotopically labeled compounds for mechanistic studies.

Basic Information

Product Name	Acetic Acid-2-13C,D4
CAS No.	285977-76-6
Molecular Formula	13C2H3COOD or C2H313COOD
Molecular Weight	65.07 g/mol (approx.)
Synonyms	Acetic-2-13C Acid-d4; Deuterated Acetic-2-13C Acid; [2-13C]Acetic Acid-d4; Acetic-d4-2-13C Acid; Perdeuterated [2-13C]Acetic Acid; (2-13C)Acetic-2,2,3,3-d4 Acid; Isotopically Labeled Acetic Acid; CD313COOD
EINECS	Contact for details

Quality Control

Our Acetic Acid-2-13C,D4 is manufactured under controlled conditions to ensure exceptional isotopic and chemical purity. Each batch undergoes rigorous analytical testing, including NMR and GC/MS, to confirm isotopic enrichment and chemical identity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (atom % 13C and % D), chemical purity, and solvent content is provided with every shipment to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place at recommended temperatures of 2°C to 8°C. For long-term stability, containers should be kept under an inert atmosphere and protected from moisture.

Specification

Item	Specification
Appearance	Clear, Colorless Liquid
Identification (NMR)	Conforms to Structure
Isotopic Purity (13C)	≥ 99 atom %
Isotopic Purity (D)	≥ 98 atom % (D, per position)
Chemical Purity (GC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.