Description

Adipoyl-D8 Chloride is a deuterated derivative of adipoyl chloride, a key acylating agent and building block in organic synthesis. This compound is specifically valued for its role as a stable isotope-labeled reagent, enabling precise tracking and analysis in research and development. It is essential for scientists and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, isotopically labeled intermediates for applications in mass spectrometry, metabolic studies, and the synthesis of deuterated polymers.

Application

• Synthesis of Deuterated Polymers: Used as a monomer or cross-linking agent to create labeled polyamides (nylons) and polyesters for structural and degradation studies.
• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of deuterated drug candidates and active pharmaceutical ingredients (APIs) for improved metabolic stability and pharmacokinetic studies.
• Analytical Chemistry & Mass Spectrometry: Employed as an internal standard or derivatization agent to enhance the accuracy and sensitivity of quantitative analysis in complex biological matrices.
• Agrochemical Development: Utilized in the creation of isotopically labeled pesticides and herbicides to study environmental fate, metabolism, and residue analysis.
• Organic Synthesis & Labeling: Acts as a versatile acyl chloride for introducing the adipoyl-D8 moiety into target molecules, facilitating mechanistic studies and pathway elucidation.
• Material Science Research: Incorporated into specialty coatings, adhesives, or composite materials to investigate molecular dynamics, diffusion, and material properties using spectroscopic techniques.

Basic Information

Product Name	Adipoyl-D8 Chloride
CAS No.	284487-62-3
Molecular Formula	C6D8Cl2O2
Molecular Weight	209.11 g/mol
Synonyms	Hexanedioyl-D8 dichloride; Adipic acid-D8 dichloride; Deuterated adipoyl chloride; Adipoyl chloride-D8; 1,6-Hexanedioyl-D8 dichloride; [D8]-Adipoyl chloride; Perdeuterated adipoyl chloride; Bis(chlorocarbonyl-D)pentane-D6
EINECS	Contact for details

Quality Control

Our Adipoyl-D8 Chloride is produced under strict quality management systems to ensure batch-to-batch consistency and high isotopic purity. Each lot undergoes comprehensive analytical testing, including NMR, GC-MS, and HPLC, to verify chemical and isotopic identity, purity, and the absence of critical impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP and ISO 9001 standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.