Description

Tetrapropyl-D28-Ammonium Bromide is a deuterium-labeled quaternary ammonium salt, a critical isotopically labeled standard for advanced analytical chemistry. Its primary value lies in enabling precise quantification and metabolic pathway tracing in complex matrices through mass spectrometry. This high-purity compound is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental science sectors who require definitive internal standards for method development and validation.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, non-interfering reference compound for the accurate quantification of quaternary ammonium compounds or structurally similar analytes in bioanalytical and environmental samples.
• Metabolic Studies & Pharmacokinetics: Used as a tracer in drug metabolism and disposition (DMPK) studies to elucidate metabolic pathways and bioavailability of pharmaceutical candidates.
• Analytical Method Development: Provides a stable, isotopically distinct marker for developing and validating highly sensitive and specific liquid chromatography-mass spectrometry (LC-MS) methods.
• Environmental Analysis: Enables the detection and precise measurement of trace levels of ionic surfactants, biocides, or other ammonium-based pollutants in water and soil samples.
• NMR Spectroscopy: Acts as a useful probe or shift reagent in nuclear magnetic resonance (NMR) studies due to the distinct magnetic properties of deuterium atoms.
• Chemical Synthesis Research: Employed as a labeled building block or catalyst in specialized synthetic chemistry research exploring reaction mechanisms.

Basic Information

Product Name	Tetrapropyl-D28-Ammonium Bromide
CAS No.	284474-84-6
Molecular Formula	C₁₂D₂₈NBr
Molecular Weight	~310.3 g/mol (Contact for exact weight based on isotopic purity)
Synonyms	Perdeuterated Tetrapropylammonium Bromide; Tetrapropylammonium-d28 Bromide; N,N,N-Tripropyl-1-propanaminium-d28 Bromide; TPA-d28 Bromide; d28-TPABr; TPABr-d28; Quaternary Ammonium Salt-d28; Isotopic Labeling Standard 284474-84-6
EINECS	Contact for details

Quality Control

Every batch of our Tetrapropyl-D28-Ammonium Bromide is manufactured and tested under strict quality management protocols. We guarantee high chemical and isotopic purity, with comprehensive characterization using NMR (¹H, ¹³C), mass spectrometry, and HPLC. A detailed Certificate of Analysis (COA) is provided with each shipment, specifying batch-specific data for identity, purity (HPLC/LC-MS), isotopic enrichment (MS), and residual solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.