Description

4-Hydroxybenzaldehyde-2,3,5,6-D4 is a deuterium-labeled analog of 4-hydroxybenzaldehyde, a key phenolic aldehyde used as a versatile building block in organic synthesis. This stable isotope-labeled compound is essential for applications requiring precise analytical tracking and quantification, such as in mass spectrometry-based studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry industries for use as an internal standard, a tracer in metabolic studies, and a precursor in the synthesis of deuterated fine chemicals.

Application

• Internal Standard for Analytical Chemistry: Used in LC-MS, GC-MS, and NMR spectroscopy for the accurate quantification of 4-hydroxybenzaldehyde and related compounds in complex matrices.
• Metabolic Pathway Tracer: Employed in pharmaceutical and biochemical research to study drug metabolism, degradation pathways, and environmental fate.
• Deuterated Pharmaceutical Intermediate: Serves as a key synthon in the development of deuterium-labeled active pharmaceutical ingredients (APIs) to potentially enhance metabolic stability and pharmacokinetic profiles.
• Agrochemical Research: Used in the synthesis and study of deuterated pesticides, herbicides, and plant growth regulators.
• Material Science Research: Acts as a precursor for deuterated polymers, ligands, and advanced organic materials where isotopic labeling is required.

Basic Information

Product Name	4-Hydroxybenzaldehyde-2,3,5,6-D4
CAS No.	284474-52-8
Molecular Formula	C7H2D4O2
Molecular Weight	126.15 g/mol
Synonyms	p-Hydroxybenzaldehyde-d4; 4-Deuteriooxybenzaldehyde-2,3,5,6-d4; 2,3,5,6-Tetradeutero-4-hydroxybenzaldehyde; Benzaldehyde, 4-hydroxy-2,3,5,6-d4-; Deutero-p-hydroxybenzaldehyde; 4-Hydroxybenzaldehyde-d4 (ring-D4); 4-Formylphenol-d4; p-Formylphenol-d4
EINECS	Contact for details

Quality Control

Our 4-Hydroxybenzaldehyde-2,3,5,6-D4 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and MS analysis, to confirm isotopic purity, chemical purity, and identity. Certificates of Analysis (COA) detailing isotopic enrichment (typically >98 atom % D), chemical purity (typically >97%), and specific analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isotopic Purity (Atom % D)	≥ 98.0% (by NMR/MS)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.