Description

6-Trifluoromethyl-1,2,3,4-Tetrahydro-Isoquinoline is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the tetrahydroisoquinoline scaffold and the electron-withdrawing trifluoromethyl group, which is critical for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, oncology, and anti-infective agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the CF3 group can enhance bioavailability and metabolic stability.
• Material Science: Acts as a building block for advanced organic materials, such as ligands for catalysis or components in organic electronic devices.
• Chemical Biology: Employed as a molecular probe or tag due to the distinctive properties imparted by the fluorine atoms.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including novel fluorination and cyclization reactions.

Basic Information

Product Name	6-Trifluoromethyl-1,2,3,4-Tetrahydro-Isoquinoline
CAS No.	284027-37-8
Molecular Formula	C10H10F3N
Molecular Weight	201.19 g/mol
Synonyms	6-(Trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6-(trifluoromethyl)isoquinoline; 6-Trifluoromethyl-1,2,3,4-tetrahydroisoquinoline; 6-CF3-THIQ; 6-Trifluoromethyl-THIQ; 6-Trifluoromethyl-1,2,3,4-THIQ; 284027-37-8
EINECS	Contact for details

Quality Control

Our 6-Trifluoromethyl-1,2,3,4-Tetrahydro-Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.