Description

(Methyl)Triphenylphosphonium Iodide-D3,13Cd3 is a high-purity, isotopically labeled organophosphorus reagent essential for advanced chemical synthesis and analytical applications. Its deuterium and carbon-13 labeling provides a critical tool for reaction mechanism studies, metabolic pathway tracing, and the synthesis of labeled compounds for use as internal standards. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require precise isotopic incorporation for their development and quality control processes.

Application

• Deuterium-Labeled Synthesis: A key reagent for the preparation of deuterium-labeled olefins via the Wittig reaction, enabling the synthesis of isotopically marked target molecules.
• Tracer Studies: Used in mechanistic and metabolic studies where tracking the fate of specific methyl groups is required, facilitated by the 13C and D labels.
• Internal Standard Production: Serves as a precursor for creating labeled internal standards used in quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy.
• Pharmaceutical Research: Employed in the discovery and development of new drug candidates, particularly for pharmacokinetic and bioavailability studies using isotope effects.
• Material Science: Can be used in the synthesis of specialized polymers or organic electronic materials where isotopic labeling is studied for property modulation.
• Academic Research: A valuable compound for university and institutional laboratories conducting fundamental research in organic chemistry and reaction dynamics.

Basic Information

Product Name	(Methyl)Triphenylphosphonium Iodide-D3,13Cd3
CAS No.	282107-30-6
Molecular Formula	C19D313C3H15PI
Molecular Weight	~430.24 g/mol (Calculated for labeled form)
Synonyms	Triphenyl(methyl-d3-13C)phosphonium iodide; Methyl-d3-13C-triphenylphosphonium iodide; (13C3)Methyltriphenylphosphonium iodide-d3; (CD3-13C)Triphenylphosphonium iodide; Phosphonium, triphenyl(methyl-d3-13C)-, iodide; Wittig Reagent-d3,13C3; Phenylphosphonium iodide, (methyl-d3-13C)triphenyl-; TPPI-d3,13C3
EINECS	Contact for details

Quality Control

Our (Methyl)Triphenylphosphonium Iodide-D3,13Cd3 is manufactured under controlled conditions to ensure high isotopic and chemical purity. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ³¹P) and mass spectrometry, to confirm isotopic enrichment, chemical identity, and purity. Certificates of Analysis (COA) detailing the specific results for each lot are provided and confirm compliance with our stringent internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider handling under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Isotopic Enrichment (MS)	≥ 98 atom % D, ≥ 99 atom % ¹³C
Purity (HPLC)	≥ 97%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.