Description

2-(4-Fluorobenzyl)-1-Oxo-3-Pyridin-3-Yl-1,2,3,4-Tetrahydroisoquinoline-4-Carboxylic Acid is a high-purity, complex heterocyclic compound serving as a critical advanced pharmaceutical intermediate. Its molecular architecture, featuring fused isoquinoline and pyridine rings with a fluorobenzyl group, makes it a valuable building block for medicinal chemistry research and development. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in neurological and oncological therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecules for biological evaluation.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Biochemical Tool Compound: Potential use in developing assays and probes for investigating specific biological pathways and enzyme interactions.

Basic Information

Product Name	2-(4-Fluorobenzyl)-1-Oxo-3-Pyridin-3-Yl-1,2,3,4-Tetrahydroisoquinoline-4-Carboxylic Acid
CAS No.	281206-13-1
Molecular Formula	C22H17FN2O3
Molecular Weight	376.38 g/mol
Synonyms	1,2,3,4-Tetrahydro-2-[(4-fluorophenyl)methyl]-1-oxo-3-(3-pyridinyl)-4-isoquinolinecarboxylic Acid; 2-[(4-Fluorophenyl)methyl]-1-oxo-3-(pyridin-3-yl)-1,2,3,4-tetrahydroisoquinoline-4-carboxylic Acid; 281206-13-1; 4-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-2-[(4-fluorophenyl)methyl]-1-oxo-3-(3-pyridinyl)-; 2-(4-Fluorobenzyl)-1-oxo-3-(3-pyridyl)-1,2,3,4-tetrahydro-4-isoquinolinecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorobenzyl)-1-Oxo-3-Pyridin-3-Yl-1,2,3,4-Tetrahydroisoquinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.