Description

6-Thiophen-3-Yl-1H-Indazole CAS NO 281203-98-3 is a high-purity heterocyclic organic compound featuring a fused indazole core linked to a thiophene moiety. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds. Its structural complexity offers significant potential for creating molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and library synthesis due to its privileged indazole-thiophene scaffold.
• Agrochemical Research: Serves as a core structure in the development of new pesticides and herbicides, leveraging its heterocyclic properties.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for catalytic systems.
• Biochemical Tool Compound: Employed in biochemical assays and as a probe for investigating enzyme inhibition and receptor binding.

Basic Information

Product Name	6-Thiophen-3-Yl-1H-Indazole
CAS No.	281203-98-3
Molecular Formula	C11H8N2S
Molecular Weight	200.26 g/mol
Synonyms	3-(1H-Indazol-6-yl)thiophene; 6-(Thiophen-3-yl)-1H-indazole; 1H-Indazole, 6-(3-thienyl)-; 6-(3-Thienyl)-1H-indazole; 6-(Thiophene-3-yl)-1H-indazole; 6-Thiophen-3-yl-1H-indazole; 6-(3-Thienyl)indazole
EINECS	Contact for details

Quality Control

Our 6-Thiophen-3-Yl-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and structural integrity, meeting the exacting standards required for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.