Description

1H-Indole-2-Carbonitrile,Octahydro-,(2S,3Ar,7As)-(9Ci) is a high-purity, stereochemically defined indole derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a rigid, functionalized scaffold for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients where stereochemistry is paramount. The CAS number for this substance is 281190-61-2.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific biological activity is required.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Material Science Research: Investigated as a monomer or functional unit for creating specialty polymers with unique optical or electronic properties.
• Academic & Contract Research: A valuable reagent for methodological studies in synthetic organic chemistry, particularly in stereoselective cyclization and functionalization reactions.

Basic Information

Product Name	1H-Indole-2-Carbonitrile,Octahydro-,(2S,3Ar,7As)-(9Ci)
CAS No.	281190-61-2
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	(2S,3aR,7aS)-Octahydro-1H-indole-2-carbonitrile; (2S,3aR,7aS)-2-Cyanooctahydroindole; (2S,3aR,7aS)-Perhydroindole-2-carbonitrile; (2S,3aR,7aS)-Hexahydropyrrolo[3,2-b]pyrrole-2-carbonitrile; (2S,3aR,7aS)-2-Cyanohexahydro-1H-pyrrolo[3,2-b]pyrrole; 281190-61-2; Stereoisomer of Octahydroindole-2-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of our 1H-Indole-2-Carbonitrile,Octahydro-,(2S,3Ar,7As)-(9Ci) is produced under strict quality management protocols to ensure exceptional purity and stereochemical integrity. We employ advanced analytical techniques, including chiral HPLC and NMR spectroscopy, to verify identity, enantiomeric excess, and impurity profiles. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with full analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.