Description

2-(4-Fluorobenzyl)-1-Oxo-3-Pyridin-4-Yl-1,2,3,4-Tetrahydroisoquinoline-4-Carboxylic Acid is a high-purity, complex heterocyclic carboxylic acid derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block and key intermediate for the research and development of novel pharmacologically active molecules. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new bioactive chemical space.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the development of new chemical entities (NCEs) at various pre-clinical and clinical stages.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for analytical method development in pharmacokinetic and metabolic studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex organic molecules for client projects.
• Academic Research: Utilized in university and institutional laboratories for cutting-edge research in organic synthesis methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-(4-Fluorobenzyl)-1-Oxo-3-Pyridin-4-Yl-1,2,3,4-Tetrahydroisoquinoline-4-Carboxylic Acid
CAS No.	278782-55-1
Molecular Formula	C26H21FN2O3
Molecular Weight	428.46 g/mol
Synonyms	1,2,3,4-Tetrahydro-2-[(4-fluorophenyl)methyl]-1-oxo-3-(4-pyridinyl)-4-isoquinolinecarboxylic Acid; 4-Carboxy-2-(4-fluorobenzyl)-3-(pyridin-4-yl)-1,2,3,4-tetrahydroisoquinolin-1-one; 278782-55-1; 2-(4-Fluorobenzyl)-1-oxo-3-(4-pyridyl)-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid; Tetrahydroisoquinoline-4-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our production of 2-(4-Fluorobenzyl)-1-Oxo-3-Pyridin-4-Yl-1,2,3,4-Tetrahydroisoquinoline-4-Carboxylic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and test results (including HPLC purity, NMR, and MS confirmation) are provided and available upon request to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.