Description

2-(2,2-Difluoro-Benzo[1,3]Dioxol-5-Yl)-Ethylamine is a high-value, fluorinated aromatic amine building block of significant interest in advanced organic synthesis. This compound is prized for its unique difluoromethylenedioxy (difluoro-benzodioxole) moiety, which can impart enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in central nervous system (CNS) therapies, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the difluoro-benzodioxole group can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Fluorine Chemistry Research: An important compound for studying structure-activity relationships (SAR) and the effects of strategic fluorine substitution.

Basic Information

Item	Detail
Product Name	2-(2,2-Difluoro-Benzo[1,3]Dioxol-5-Yl)-Ethylamine
CAS No.	278183-65-6
Molecular Formula	C9H9F2NO2
Molecular Weight	201.17 g/mol
Synonyms	5-(2-Aminoethyl)-2,2-difluoro-1,3-benzodioxole; 2,2-Difluoro-5-(2-aminoethyl)-1,3-benzodioxole; 2-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)ethan-1-amine; 2-(2,2-Difluoro-1,3-benzodioxol-5-yl)ethylamine; 2,2-Difluoro-1,3-benzodioxole-5-ethylamine; 5-(2-Aminoethyl)-2,2-difluorobenzodioxole; Difluoro-Benzodioxole Ethylamine
EINECS	Contact for details

Quality Control

Every batch of 2-(2,2-Difluoro-Benzo[1,3]Dioxol-5-Yl)-Ethylamine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.