Description

1,2,8-Indolizinetriol,8A-Ethyloctahydro-,(1S,2R,8R,8Ar)-(9Ci) is a complex, stereochemically defined indolizine derivative, a class of compounds known for their diverse biological activities and utility as advanced synthetic intermediates. This high-purity chiral compound is critical for research and development in pharmaceutical chemistry, where precise molecular structure is paramount for efficacy and safety. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for use in asymmetric synthesis, medicinal chemistry programs, and as a potential scaffold for novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, particularly in therapeutic areas targeting complex diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new biological targets.
• Asymmetric Synthesis: Employed as a sophisticated reagent or intermediate in catalytic and stoichiometric asymmetric transformations to introduce multiple stereocenters.
• Agrochemical Development: Investigated as a precursor for novel, biologically active compounds in crop protection and pest management research.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex natural product analogs and specialty chemicals.
• Biochemical Tool Compound: Potentially used in biochemical assays to study enzyme inhibition or receptor binding mechanisms.

Basic Information

Product Name	1,2,8-Indolizinetriol,8A-Ethyloctahydro-,(1S,2R,8R,8Ar)-(9Ci)
CAS No.	277755-43-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(1S,2R,8R,8aR)-8a-Ethyloctahydro-1,2,8-indolizinetriol; 8a-Ethyloctahydro-1,2,8-indolizinetriol, (1S,2R,8R,8aR)-; 277755-43-8; Indolizinetriol derivative; Chiral indolizine triol; Octahydroindolizinetriol
EINECS	Contact for details

Quality Control

Every batch of our 1,2,8-Indolizinetriol,8A-Ethyloctahydro-,(1S,2R,8R,8Ar)-(9Ci) is produced and controlled under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and stereochemical purity, meeting the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation. Recommended long-term storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.