Description

Benzenemethanol, 2-Chloro-3-Hydroxy- is a halogenated benzyl alcohol derivative, a versatile chiral building block in advanced organic synthesis. Its unique structure, featuring both a chloro and a hydroxy substituent on the aromatic ring, makes it a critical intermediate for constructing complex molecules with high stereochemical purity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of specialty polymers and liquid crystals due to its rigid, substituted benzene core.
• Fine Chemical Production: Acts as a building block for dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	Benzenemethanol, 2-Chloro-3-Hydroxy-
CAS No.	277331-17-6
Molecular Formula	C7H7ClO2
Molecular Weight	158.58 g/mol
Synonyms	2-Chloro-3-hydroxybenzyl alcohol; (2-Chloro-3-hydroxyphenyl)methanol; 3-Hydroxy-2-chlorobenzyl alcohol; 2-Chloro-3-hydroxybenzenemethanol; 1-(2-Chloro-3-hydroxyphenyl)methanol; Benzenemethanol, 2-chloro-3-hydroxy-; α-Hydroxy-2-chloro-3-methylbenzene (common name variant)
EINECS	Contact for details

Quality Control

Every batch of Benzenemethanol, 2-Chloro-3-Hydroxy- is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and scale-up activities. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, and NMR is supplied with each shipment. Custom synthesis and purification to meet specific project specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.