Description

1-Azabicyclo[3.2.1]Octan-6-Ol,(1S,5R,6S)-(9Ci) is a high-purity, stereochemically defined bicyclic amino alcohol building block. This compound is valued for its rigid, three-dimensional scaffold, which is crucial for imparting specific biological activity and physicochemical properties in advanced molecular design. It serves as a critical chiral intermediate for pharmaceutical research and development, particularly in the synthesis of active pharmaceutical ingredients (APIs) and novel therapeutic agents targeting the central nervous system and other disease areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and commercial synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Used as a privileged scaffold in drug discovery for constructing molecules with enhanced binding affinity and metabolic stability.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and biological pathways.
• Agrochemical Research: Serves as a building block for developing novel crop protection agents with specific modes of action.
• Academic & Industrial R&D: A valuable compound for methodological development and exploring new chemical space in both academic and industrial research settings.

Basic Information

Product Name	1-Azabicyclo[3.2.1]Octan-6-Ol,(1S,5R,6S)-(9Ci)
CAS No.	277327-28-3
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	(1S,5R,6S)-6-Hydroxy-1-azabicyclo[3.2.1]octane; (1S,5R,6S)-1-Azabicyclo[3.2.1]octan-6-ol; endo-6-Hydroxy-1-azabicyclo[3.2.1]octane; Tropan-6-ol derivative; Bicyclic amino alcohol; 1-Azabicyclo[3.2.1]octan-6-ol, (1S,5R,6S)-; 277327-28-3
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[3.2.1]Octan-6-Ol,(1S,5R,6S)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.