Description

Benzenemethanol, α-Ethynyl-4-Hydroxy- (9Ci) is a specialized organic compound featuring a benzenemethanol core substituted with an ethynyl and a hydroxy group. This unique structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for fine chemical synthesis. It is primarily utilized by research institutions and pharmaceutical R&D departments for the development of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Organic Synthesis Reagent: Used in research-scale and pilot-scale reactions, including Sonogashira coupling and other cross-coupling methodologies.
• Ligand Precursor: Serves as a starting material for the preparation of specialized ligands used in catalysis and material science.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals for agrochemical and material science applications.
• Academic & Industrial Research: A critical compound for exploring new synthetic pathways and developing novel chemical entities in R&D settings.

Basic Information

Product Name	Benzenemethanol, α-Ethynyl-4-Hydroxy- (9Ci)
CAS No.	276884-28-7
Molecular Formula	C9H8O2
Molecular Weight	148.16 g/mol
Synonyms	4-Hydroxy-α-ethynylbenzenemethanol; 1-(4-Hydroxyphenyl)-2-propyn-1-ol; α-Ethynyl-4-hydroxybenzenemethanol; 4-Hydroxybenzeneethynylmethanol; (4-Hydroxyphenyl)(prop-2-yn-1-yl)methanol; 4-Hydroxy-α-ethynylbenzyl alcohol
EINECS	Contact for details

Quality Control

Our Benzenemethanol, α-Ethynyl-4-Hydroxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.