Description

1,3-Dihydro-5-Fluoro-4-Iodo-2H-Indol-2-One is a high-value halogenated indole derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both fluorine and iodine substituents, makes it an essential intermediate for creating novel compounds with targeted biological activity. This product is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials. We supply this compound with a focus on high purity, batch-to-batch consistency, and reliable global logistics to support your complex synthesis projects.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and pesticides, leveraging its halogenated indole core.
• Material Science: Serves as a precursor for advanced organic electronic materials and functional dyes.
• Chemical Biology: Employed as a probe or labeling agent in biochemical research due to the reactivity of the iodine moiety.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including cross-coupling reactions and heterocyclic chemistry.
• Custom Synthesis: A starting material for the contract manufacturing of complex, tailor-made molecules for various industries.

Basic Information

Product Name	1,3-Dihydro-5-Fluoro-4-Iodo-2H-Indol-2-One
CAS No.	275386-75-9
Molecular Formula	C8H5FINO
Molecular Weight	277.04 g/mol
Synonyms	5-Fluoro-4-iodooxindole; 4-Iodo-5-fluoroindolin-2-one; 5-Fluoro-4-iodo-1,3-dihydro-2H-indol-2-one; 5-Fluoro-4-iodooxindole; 4-Iodo-5-fluoro-2-oxindole; 275386-75-9; AI3-31036; AKOS005258023; ZINC000003869756; SCHEMBL2182741.
EINECS	Contact for details

Quality Control

Our 1,3-Dihydro-5-Fluoro-4-Iodo-2H-Indol-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.