Description

1,5-Diazabicyclo[4.2.0]Octa-3,5-Diene,2,8-Dimethyl-,(2R,8R)-Rel-(9Ci) is a sophisticated chiral bicyclic diamine derivative with a defined stereochemistry, serving as a high-value building block and chiral ligand in advanced organic synthesis. Its unique constrained geometry and nitrogen functionality make it a critical component for constructing complex molecular architectures with precise stereocontrol. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in neurological and antiviral drug candidates.
• Asymmetric Catalysis Ligand: Used as a precursor or direct ligand in transition metal catalysis (e.g., for palladium or rhodium) to induce high enantioselectivity in C-C and C-N bond-forming reactions.
• Agrochemical Synthesis: Employed in the research and development of novel, stereospecific herbicides, fungicides, and plant growth regulators.
• Material Science Monomer: Acts as a functional monomer for creating polymers with specific chiral or nitrogen-containing functionalities for advanced material applications.
• Academic & R&D: A valuable tool for methodological development in organic chemistry and medicinal chemistry research within university and corporate laboratories.
• Fine Chemical Production: Serves as a building block for manufacturing other high-purity, complex specialty chemicals and fine chemicals.

Basic Information

Item	Details
Product Name	1,5-Diazabicyclo[4.2.0]Octa-3,5-Diene,2,8-Dimethyl-,(2R,8R)-Rel-(9Ci)
CAS No.	274917-79-2
Molecular Formula	C8H12N2
Molecular Weight	136.20 g/mol
Synonyms	(2R,8R)-rel-2,8-Dimethyl-1,5-diazabicyclo[4.2.0]octa-3,5-diene; 2,8-Dimethyl-1,5-diazabicyclo[4.2.0]octa-3,5-diene, (2R,8R)-rel-; (rel-(2R,8R))-2,8-Dimethyl-1,5-diazabicyclo[4.2.0]octa-3,5-diene; Bicyclic Diamine Derivative; Chiral Diazabicyclooctadiene; CAS 274917-79-2
EINECS	Contact for details

Quality Control

Every batch of our 1,5-Diazabicyclo[4.2.0]Octa-3,5-Diene,2,8-Dimethyl-,(2R,8R)-Rel-(9Ci) is manufactured under strict quality management systems and undergoes comprehensive analytical characterization to ensure identity, purity, and enantiomeric excess. Our standard R&D and custom synthesis grades are supported by full analytical documentation. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere if the material is highly purified to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.