Description

Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 5-Hydroxy- (9Ci) is a high-purity, functionalized carboxylic acid derivative of norbornane, characterized by its unique bicyclic, strained ring structure and hydroxyl group. This compound serves as a versatile and critical chiral building block in advanced organic synthesis, enabling the construction of complex molecular architectures with precise stereochemistry. It is primarily required by pharmaceutical R&D, agrochemical, and specialty chemical industries for the development of novel active ingredients and high-value intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its rigid bicyclic framework.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty polymers and advanced organic materials with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process development.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fragrance and flavor ingredients.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 5-Hydroxy- (9Ci)
CAS No.	274690-03-8
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	5-Hydroxybicyclo[2.2.1]heptane-2-carboxylic acid; 5-Hydroxynorbornane-2-carboxylic acid; endo-5-Hydroxybicyclo[2.2.1]heptane-2-carboxylic acid; 2-Norbornanecarboxylic acid, 5-hydroxy-; Bicyclo[2.2.1]heptane-2-carboxylic acid, 5-hydroxy-; 5-Hydroxy-2-norbornanecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 5-Hydroxy- (9Ci) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation to ensure it meets exacting R&D and production standards. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.