Description

Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 6-Hydroxy-, (2R,6R)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its rigid bicyclic framework and functional group array make it a valuable precursor for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought after by research institutions and pharmaceutical developers for applications in medicinal chemistry, asymmetric catalysis, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Synthesis: Serves as a precursor for chiral ligands, auxiliaries, and catalysts used in enantioselective transformations.
• Advanced Material Research: Used in the synthesis of specialty polymers and liquid crystals where a rigid, functionalized core structure is required.
• Agrochemical Development: Employed as a building block for novel, biologically active compounds with specific stereochemical requirements.
• Academic & R&D: A valuable tool for methodological studies in organic chemistry and for probing structure-activity relationships (SAR).
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex, naturally-inspired odorants and flavor molecules.

Basic Information

Item	Detail
Product Name	Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 6-Hydroxy-, (2R,6R)-Rel- (9Ci)
CAS No.	274690-02-7
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	(2R,6R)-6-Hydroxybicyclo[2.2.1]heptane-2-carboxylic Acid; rel-(2R,6R)-6-Hydroxy-2-norbornanecarboxylic Acid; (1R,4R)-4-Hydroxybicyclo[2.2.1]heptane-1-carboxylic Acid; endo,exo-6-Hydroxybicyclo[2.2.1]heptane-2-carboxylic Acid; Bicyclo[2.2.1]heptane-2-carboxylic acid, 6-hydroxy-, (1R,4R)-rel-; Norcamphor carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 6-Hydroxy-, (2R,6R)-Rel- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure consistent identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all relevant specifications are provided with each shipment. We support compliance with cGMP and REACH requirements for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.