Description

Bicyclo[3.2.1]Octane-6-Carbonitrile, 4-Hydroxy-, (6S)- (9Ci) is a high-purity, chiral bicyclic nitrile derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated pharmaceutical intermediate and a versatile chiral building block for constructing complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Chiral Building Block: Used in asymmetric synthesis to introduce the bicyclo[3.2.1]octane scaffold with defined stereochemistry for medicinal chemistry and chemical biology.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, or insecticides with specific stereochemical requirements for enhanced activity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique thermal or mechanical properties due to its rigid, three-dimensional structure.
• Academic & Process Chemistry: Used in methodological studies and scale-up process development for complex organic molecules.

Basic Information

Item	Detail
Product Name	Bicyclo[3.2.1]Octane-6-Carbonitrile, 4-Hydroxy-, (6S)- (9Ci)
CAS No.	274263-11-5
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	(6S)-4-Hydroxybicyclo[3.2.1]octane-6-carbonitrile; (6S)-4-Hydroxy-6-bicyclo[3.2.1]octanecarbonitrile; 4-Hydroxybicyclo[3.2.1]octane-6-carbonitrile, (6S)-; Bicyclo[3.2.1]octane-6-carbonitrile, 4-hydroxy-, (6S)-; (6S)-4-Hydroxy-6-cyanobicyclo[3.2.1]octane; 274263-11-5; (6S)-4-Hydroxy-6-bicyclo[3.2.1]octanenitrile
EINECS	Contact for details

Quality Control

Our Bicyclo[3.2.1]Octane-6-Carbonitrile, 4-Hydroxy-, (6S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination and impurity profiling, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, maintaining the material at 2-8°C under an inert atmosphere is recommended to preserve stability and chiral integrity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.