Description

1H-Indole-1,5-Dicarboxylic Acid, 1-(1,1-Dimethylethyl) 5-Methyl Ester is a high-purity, synthetically valuable indole derivative, serving as a critical protected intermediate in advanced organic synthesis. Its primary value lies in enabling the controlled functionalization of the indole scaffold, a privileged structure in medicinal chemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex molecules for drug discovery and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel indole-based active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides that leverage the indole core for biological activity.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and natural product analogs.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors, dyes, and functional polymers due to its conjugated indole structure.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	1H-Indole-1,5-Dicarboxylic Acid, 1-(1,1-Dimethylethyl) 5-Methyl Ester
CAS No.	272438-11-6
Molecular Formula	C16H19NO4
Molecular Weight	289.33 g/mol
Synonyms	1-(tert-Butyl) 5-methyl 1H-indole-1,5-dicarboxylate; tert-Butyl methyl 1H-indole-1,5-dicarboxylate; 1-tert-Butoxycarbonylindole-5-carboxylic acid methyl ester; 1-Boc-indole-5-carboxylic acid methyl ester; Methyl 1-Boc-1H-indole-5-carboxylate; 1H-Indole-1,5-dicarboxylic acid, 1-(1,1-dimethylethyl) 5-methyl ester; 5-(Methoxycarbonyl)-1H-indole-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-1,5-Dicarboxylic Acid, 1-(1,1-Dimethylethyl) 5-Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.