Description

(2-(4-Bromophenyl)Ethynyl)Triisopropylsilane is a specialized organosilicon building block featuring a brominated aromatic alkyne moiety protected by a triisopropylsilyl (TIPS) group. This compound matters for its dual functionality, serving as a versatile intermediate in complex organic synthesis where selective deprotection and cross-coupling reactions are required. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring Sonogashira or other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate complex aromatic-alkyne structures.
• Material Science & OLED Development: Serves as a precursor for creating conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and other electronic materials.
• Ligand & Catalyst Preparation: Employed in the synthesis of sophisticated ligands and organometallic catalysts for asymmetric synthesis.
• Academic & Industrial R&D: A valuable reagent for methodology development and exploring new synthetic pathways in organic chemistry laboratories.
• Custom Synthesis & Scale-up: Supplied for contract research and manufacturing projects requiring gram to kilogram quantities of this specific protected alkyne.

Basic Information

Product Name	(2-(4-Bromophenyl)Ethynyl)Triisopropylsilane
CAS No.	271242-20-7
Molecular Formula	C17H25BrSi
Molecular Weight	337.37 g/mol
Synonyms	1-Bromo-4-[(triisopropylsilyl)ethynyl]benzene; 4-Bromophenyl(triisopropylsilyl)acetylene; TIPS-Protected 4-Bromophenylacetylene; (4-Bromophenylethynyl)triisopropylsilane; 1-Bromo-4-(2-triisopropylsilylethynyl)benzene; (p-Bromophenylethynyl)triisopropylsilane; 4-Bromo-((triisopropylsilyl)ethynyl)benzene; 4-Bromophenylethynyltriisopropylsilane
EINECS	Contact for details

Quality Control

Our (2-(4-Bromophenyl)Ethynyl)Triisopropylsilane is produced and tested under strict quality management protocols. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with key parameters including assay (by GC/HPLC), identity confirmation (by IR, NMR), and impurity profiles. Our quality commitment supports applications requiring high-purity synthetic intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.