Description

1,3-Dimethyluracil-5-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel uracil-based nucleoside analogs and other heterocyclic compounds with potential therapeutic activity.
• Agrochemical Research: Used in the discovery and development of new agrochemicals, including herbicides and fungicides, where the uracil moiety is a common bioactive scaffold.
• Material Science: Employed in the synthesis of organic electronic materials, such as those used in OLEDs or sensors, due to its ability to introduce the boronic ester functional group.
• Chemical Biology & Probe Development: Acts as a versatile handle for bioconjugation and the creation of molecular probes for studying biological processes.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and for producing custom compounds in contract research organizations (CROs).

Basic Information

Product Name	1,3-Dimethyluracil-5-Boronic Acid Pinacol Ester
CAS No.	269410-01-7
Molecular Formula	C₁₃H₁₉BN₂O₄
Molecular Weight	278.11 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione; 1,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)uracil; 1,3-Dimethyl-5-boronouracil pinacol ester; 5-Borono-1,3-dimethyluracil pinacol ester; DMU-BPin
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyluracil-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR (¹H, ¹³C, ¹¹B), and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and easily oxidized nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.