Description

2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is a high-purity boronic ester derivative, serving as a crucial synthetic intermediate in modern organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing phenolic biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aromatic coupling.
• Material Science: Precursor for creating organic electronic materials, such as polymers for OLEDs and organic photovoltaics, where controlled coupling is critical.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel bidentate ligands and organometallic catalysts.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new C-C bond formation methodologies and constructing molecular libraries.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals and dyes.

Basic Information

Item	Details
Product Name	2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol
CAS No.	269409-97-4
Molecular Formula	C12H17BO3
Molecular Weight	220.07 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; Phenol, 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2-Hydroxyphenylboronic acid pinacol ester; (2-Hydroxyphenyl)boronic acid pinacol ester; 2-Pinacolatoborylphenol; 2-(Pinacolatoboryl)phenol; 2-Phenolpinacolboronate
EINECS	Contact for details

Quality Control

Our 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.