Description

3-Amino-5-Aminomethyl-1H-Indazole Hydrochloride is a high-purity, functionalized indazole derivative offered as a hydrochloride salt for enhanced stability and handling. This compound serves as a critical pharmaceutical intermediate and research chemical in the development of novel therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for synthesizing targeted molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its versatile amino and aminomethyl functional groups.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value compounds.
• Library Synthesis for Drug Discovery: A valuable reactant for generating diverse compound libraries in high-throughput screening campaigns.

Basic Information

Product Name	3-Amino-5-Aminomethyl-1H-Indazole Hydrochloride
CAS No.	267876-21-1
Molecular Formula	C8H11ClN4
Molecular Weight	198.65 g/mol
Synonyms	5-(Aminomethyl)-1H-indazol-3-amine hydrochloride; 1H-Indazole-3-amine, 5-(aminomethyl)-, hydrochloride; 3-Amino-5-(aminomethyl)indazole HCl; 5-Aminomethyl-3-aminoindazole hydrochloride; 3,5-Diamino-1H-indazole hydrochloride (ambiguous); AAIA HCl; 267876-21-1
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Aminomethyl-1H-Indazole Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting research and pharmaceutical-grade standards. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.