Description

1H-Benzimidazole, 5-(Azidomethyl)- (9Ci) is a specialized heterocyclic organic compound featuring a reactive azidomethyl functional group. This structural motif makes it a valuable high-purity building block for advanced synthesis in pharmaceutical and materials research. It is primarily utilized by R&D chemists and process development scientists working in medicinal chemistry, bioconjugation, and polymer science to create novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or requiring click chemistry for bioconjugation.
• Bioconjugation Reagent: Used in the development of antibody-drug conjugates (ADCs), diagnostic probes, and other biopharmaceuticals via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
• Polymer & Materials Science: Serves as a functional monomer or cross-linking agent for creating advanced polymers with specific thermal, mechanical, or responsive properties.
• Agrochemical Research: Employed in the design and synthesis of new active ingredients for crop protection with potential novel modes of action.
• Chemical Biology Probe Development: Used to create activity-based probes for studying enzyme function and protein interactions within biological systems.
• Ligand Synthesis for Catalysis: Acts as a scaffold for constructing complex ligands used in homogeneous catalysis and asymmetric synthesis.

Basic Information

Product Name	1H-Benzimidazole, 5-(Azidomethyl)- (9Ci)
CAS No.	267875-43-4
Molecular Formula	C8H7N5
Molecular Weight	173.17 g/mol
Synonyms	5-(Azidomethyl)-1H-benzimidazole; 5-(Azidomethyl)benzimidazole; 1H-Benzimidazole, 5-(azidomethyl)-; Benzimidazole, 5-(azidomethyl)-; Azidomethylbenzimidazole; 267875-43-4; 5-Azidomethylbenzimidazole
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole, 5-(Azidomethyl)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality systems support development and cGMP manufacturing requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.