Description

6-(Aminomethyl)-1H-Indazol-3-Amine Dihydrochloride is a high-purity, pharmaceutically relevant chemical building block. This compound is a key intermediate in the synthesis of complex molecules, particularly for research and development in medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of novel therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted cancer therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for drug discovery programs.
• Kinase Inhibitor Development: Serves as a core scaffold or precursor in the design and synthesis of potent and selective kinase inhibitors.
• Bioconjugation & Probe Synthesis: The aminomethyl group allows for functionalization and conjugation, useful for creating biochemical probes and labeled compounds.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex heterocyclic systems with pharmaceutical potential.

Basic Information

Product Name	6-(Aminomethyl)-1H-Indazol-3-Amine Dihydrochloride
CAS No.	267413-33-2
Molecular Formula	C8H12Cl2N4
Molecular Weight	235.11 g/mol
Synonyms	3-Amino-1H-indazole-6-methanamine dihydrochloride; 6-(Aminomethyl)-1H-indazol-3-amine dihydrochloride; 1H-Indazol-3-amine, 6-(aminomethyl)-, dihydrochloride; 6-(Aminomethyl)indazol-3-amine dihydrochloride; 267413-33-2; 6-Aminomethyl-1H-indazol-3-ylamine dihydrochloride
EINECS	Contact for details

Quality Control

Our 6-(Aminomethyl)-1H-Indazol-3-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.