Description

4-Bromo-3-Methyl-2-Thiophenecarbonyl Chloride is a high-value, reactive organosulfur building block primarily used in advanced organic synthesis. This compound is critical for the efficient introduction of functionalized thiophene moieties into complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides that incorporate the thiophene heterocycle for enhanced bioactivity and environmental profile.
• Material Science & Organic Electronics: Serves as a monomer or building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis, enabling novel cross-coupling and other transformative reactions.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on heterocyclic chemistry, medicinal chemistry, and the exploration of new chemical space.

Basic Information

Product Name	4-Bromo-3-Methyl-2-Thiophenecarbonyl Chloride
CAS No.	265652-36-6
Molecular Formula	C7H4BrClOS
Molecular Weight	251.53 g/mol
Synonyms	4-Bromo-3-methylthiophene-2-carbonyl chloride; 2-Thiophenecarbonyl chloride, 4-bromo-3-methyl-; 4-Bromo-3-methyl-2-thiophenecarboxylic acid chloride; 3-Methyl-4-bromothiophene-2-carbonyl chloride; 4-Bromo-3-methylthiophene-2-carboxylic acid chloride; 265652-36-6; 4-Bromo-3-methyl-2-thiophenecarboxoyl chloride
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Methyl-2-Thiophenecarbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry standards for research and process chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.