Description

7-Bromo-4,4-Dimethyl-1,2,3,4-Tetrahydro-Isoquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its brominated tetrahydroisoquinoline core structure. This compound is a critical building block in the synthesis of complex molecules, offering a versatile handle for further functionalization in medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its reactive bromine substituent.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic compounds and natural product analogs.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Material Science: Can be investigated as a monomer or functional component in the development of specialty polymers and advanced materials.

Basic Information

Product Name	7-Bromo-4,4-Dimethyl-1,2,3,4-Tetrahydro-Isoquinoline
CAS No.	264602-74-6
Molecular Formula	C11H14BrN
Molecular Weight	240.14 g/mol
Synonyms	7-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline; 4,4-Dimethyl-7-bromo-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-7-bromo-4,4-dimethylisoquinoline; 7-Bromo-4,4-dimethyl-3,4-dihydro-1H-isoquinoline; 264602-74-6
EINECS	Contact for details

Quality Control

Our 7-Bromo-4,4-Dimethyl-1,2,3,4-Tetrahydro-Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.