Description

Ethyl 1-((1,3-Dioxoisoindolin-2-yl)methyl)-6,7-dimethoxyisoquinoline-4-carboxylate is a high-purity, advanced pharmaceutical intermediate designed for critical synthesis pathways. This compound is valued for its role as a key building block in the development of complex bioactive molecules, particularly within medicinal chemistry research. It is primarily sought by R&D laboratories and pharmaceutical manufacturers engaged in the synthesis of novel therapeutic agents, including potential candidates for oncology and neurological disorders.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in the construction of complex heterocyclic systems, particularly those containing fused isoquinoline and phthalimide moieties.
• Biochemical Research: Potential use in the development of enzyme inhibitors or receptor modulators for biochemical assays.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	Ethyl 1-((1,3-Dioxoisoindolin-2-yl)methyl)-6,7-dimethoxyisoquinoline-4-carboxylate
CAS No.	264188-67-2
Molecular Formula	C24H22N2O6
Molecular Weight	434.44 g/mol
Synonyms	1-[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-6,7-dimethoxy-4-isoquinolinecarboxylic acid ethyl ester; Ethyl 1-(phthalimidomethyl)-6,7-dimethoxyisoquinoline-4-carboxylate; 6,7-Dimethoxy-1-[(1,3-dioxoisoindolin-2-yl)methyl]isoquinoline-4-carboxylic acid ethyl ester; 264188-67-2; UNII-7V8G3F8X7R; 7V8G3F8X7R; Ethyl 1-(N-phthaloylmethyl)-6,7-dimethoxy-4-isoquinolinecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 1-((1,3-Dioxoisoindolin-2-yl)methyl)-6,7-dimethoxyisoquinoline-4-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive (store away from light). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.