Description

1-Isoquinolineacetic Acid, 1,2,3,4-Tetrahydro-6,7-Dimethoxy-, Methyl Ester is a high-purity synthetic intermediate belonging to the tetrahydroisoquinoline class of compounds. This compound matters as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a versatile scaffold for further functionalization. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in advanced organic synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential therapeutic agents, particularly those targeting the central nervous system (CNS).
• Agrochemical Research: Used in the development of new crop protection agents and plant growth regulators due to its complex heterocyclic structure.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing more complex nitrogen-containing heterocycles and natural product analogs.
• Ligand and Catalyst Development: Acts as a starting material for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions.

Basic Information

Item	Details
Product Name	1-Isoquinolineacetic Acid, 1,2,3,4-Tetrahydro-6,7-Dimethoxy-, Methyl Ester
CAS No.	263570-28-1
Molecular Formula	C₁₄H₁₉NO₄
Molecular Weight	265.31 g/mol
Synonyms	Methyl 1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolineacetate; 1,2,3,4-Tetrahydro-6,7-dimethoxy-1-isoquinolineacetic acid methyl ester; 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-1-acetic acid methyl ester; THIQ derivative; Tetrahydroisoquinoline acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1-Isoquinolineacetic Acid, 1,2,3,4-Tetrahydro-6,7-Dimethoxy-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.