Description

tert-Butyl 4-Iodobutylcarbamate is a versatile and high-purity chemical intermediate designed for advanced organic synthesis. This compound is valued for its reactive iodine and protected amine functionalities, enabling precise molecular construction in complex chemical pathways. It is an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a functionalized butylamine chain.
• Peptidomimetics & Bioconjugation: Used in the construction of peptide analogs and for linking molecules to biological targets via the reactive iodoalkyl group.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the development of specialty polymers, dendrimers, and functionalized surfaces.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed cross-coupling reactions (e.g., Heck, Sonogashira) to form carbon-carbon bonds.
• Nucleoside & Nucleotide Chemistry: Useful for the alkylation and modification of nucleosides in medicinal chemistry programs.

Basic Information

Product Name	tert-Butyl 4-Iodobutylcarbamate
CAS No.	262278-40-0
Molecular Formula	C9H18INO2
Molecular Weight	299.15 g/mol
Synonyms	4-Iodo-N-(tert-butoxycarbonyl)butan-1-amine; N-Boc-4-iodobutylamine; 1-Boc-amino-4-iodobutane; tert-Butyl (4-iodobutyl)carbamate; N-(tert-Butoxycarbonyl)-4-iodobutylamine; Boc-4-Iodobutylamine; 4-Iodobutylcarbamic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Iodobutylcarbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.