Description

1-(Bromomethyl)-2-(Trifluoromethyl)-4-Methylbenzene is a versatile and high-value aromatic building block containing both bromomethyl and trifluoromethyl functional groups. This compound is critical for introducing these key moieties into target molecules, enabling the synthesis of advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought after by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in the synthesis of molecules with trifluoromethyl groups known to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group often contributes to improved efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials used in displays and lighting technologies.
• Functional Polymer Monomer: Employed to incorporate aromatic, brominated, and fluorinated units into polymers to tailor properties like thermal stability, chemical resistance, and refractive index.
• Cross-Coupling Reactions: The bromomethyl group acts as an excellent handle for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Organic Synthesis Reagent: Utilized in academic and industrial R&D labs for the preparation of complex fluorinated aromatic compounds and fine chemicals.

Basic Information

Product Name	1-(Bromomethyl)-2-(Trifluoromethyl)-4-Methylbenzene
CAS No.	261952-18-5
Molecular Formula	C9H8BrF3
Molecular Weight	253.06 g/mol
Synonyms	2-(Trifluoromethyl)-4-methylbenzyl bromide; 4-Methyl-2-(trifluoromethyl)benzyl bromide; α-Bromo-2-trifluoromethyl-p-xylene; 2-Trifluoromethyl-4-methylbenzyl bromide; 1-(Bromomethyl)-2-trifluoromethyl-4-methylbenzene; p-Xylene, α-bromo-2-trifluoromethyl-; (2-Trifluoromethyl-4-methylphenyl)methyl bromide
EINECS	Contact for details

Quality Control

Our 1-(Bromomethyl)-2-(Trifluoromethyl)-4-Methylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and reactivity, it is recommended to handle under an inert atmosphere for extended storage periods.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.