Description

tert-Butyl 5-Bromoindoline-1-Carboxylate is a high-purity, protected indoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for use in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides.
• Material Science: Potential monomer or precursor for functionalized polymers and advanced organic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and novel reaction exploration.

Basic Information

Product Name	tert-Butyl 5-Bromoindoline-1-Carboxylate
CAS No.	261732-38-1
Molecular Formula	C13H16BrNO2
Molecular Weight	298.18 g/mol
Synonyms	1-BOC-5-Bromoindoline; 5-Bromo-1-(tert-butoxycarbonyl)indoline; 5-Bromoindoline-1-carboxylic acid tert-butyl ester; tert-Butyl 5-bromo-2,3-dihydro-1H-indole-1-carboxylate; 1H-Indole-1-carboxylic acid, 5-bromo-2,3-dihydro-, 1,1-dimethylethyl ester; BOC-5-Bromoindoline; 5-Bromo-N-BOC-indoline
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Bromoindoline-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.