Description

5-(4-tert-Butylphenyl)-4-[3-(Trifluoromethyl)Phenyl]-1,2,4-Triazole-3-Thiol is a high-value, functionalized triazole derivative that serves as a critical building block in advanced chemical synthesis. Its molecular architecture, featuring both tert-butyl and trifluoromethyl phenyl substituents, provides unique steric and electronic properties essential for developing high-performance materials and active pharmaceutical ingredients. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced biological activity and material characteristics.

Application

• As a key pharmaceutical intermediate in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Utilized as a versatile agrochemical intermediate for developing next-generation herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profiles.
• Serves as a ligand precursor or catalyst component in organometallic chemistry and cross-coupling reactions for fine chemical synthesis.
• Employed in material science research for the development of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and charge-transport layers.
• Acts as a corrosion inhibitor additive in advanced coating formulations for industrial and automotive applications.
• Used in academic and industrial R&D for exploring structure-activity relationships (SAR) in medicinal chemistry programs.

Basic Information

Product Name	5-(4-tert-Butylphenyl)-4-[3-(Trifluoromethyl)Phenyl]-1,2,4-Triazole-3-Thiol
CAS No.	261633-26-5
Molecular Formula	C19H18F3N3S
Molecular Weight	377.43 g/mol
Synonyms	5-(4-tert-Butylphenyl)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazole-3-thiol; 4-(3-(Trifluoromethyl)phenyl)-5-(4-(tert-butyl)phenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione; 1,2,4-Triazole-3-thiol, 5-(4-(1,1-dimethylethyl)phenyl)-4-(3-(trifluoromethyl)phenyl)-; TBTFPT; 4-(3-Trifluoromethylphenyl)-5-(4-tert-butylphenyl)-1,2,4-triazole-3-thiol
EINECS	Contact for details

Quality Control

Our production of 5-(4-tert-Butylphenyl)-4-[3-(Trifluoromethyl)Phenyl]-1,2,4-Triazole-3-Thiol adheres to a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your internal specifications and Good Manufacturing Practice (GMP) principles where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.