Description

1-Diethoxymethylindole-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound matters for its critical role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily needed by R&D chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the indole core structure for biological activity.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds and specialty chemicals.
• Material Science: Potential monomer or precursor for the development of functional organic materials and dyes.
• Academic & Contract Research: Essential reagent for methodological studies in organic synthesis and medicinal chemistry research at universities and CROs.

Basic Information

Product Name	1-Diethoxymethylindole-5-Carbonitrile
CAS No.	261177-22-4
Molecular Formula	C₁₄H₁₆N₂O₂
Molecular Weight	244.29 g/mol
Synonyms	5-Cyano-1-(diethoxymethyl)indole; 1-(Diethoxymethyl)-1H-indole-5-carbonitrile; 1H-Indole-5-carbonitrile, 1-(diethoxymethyl)-; Indole-5-carbonitrile, 1-diethoxymethyl-; 1-Diethoxymethyl-5-cyanoindole; 261177-22-4; 1-DEMI-5-CN
EINECS	Contact for details

Quality Control

Our 1-Diethoxymethylindole-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.