Description

1H-Indole-2-Carboxylic Acid, 6-Chloro-7-Fluoro- is a high-value halogenated indole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its precise molecular structure makes it indispensable for constructing complex pharmacophores, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical research, and the synthesis of specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides, fungicides, or plant growth regulators.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for exploratory synthetic projects and methodological studies.

Basic Information

Product Name	1H-Indole-2-Carboxylic Acid, 6-Chloro-7-Fluoro-
CAS No.	259860-07-6
Molecular Formula	C9H5ClFNO2
Molecular Weight	213.59 g/mol
Synonyms	6-Chloro-7-fluoro-1H-indole-2-carboxylic acid; 6-Chloro-7-fluoroindole-2-carboxylic acid; 2-Carboxy-6-chloro-7-fluoroindole; 6-Chloro-7-fluoro-2-indolecarboxylic acid; 259860-07-6; 6-Cl-7-F-1H-indole-2-COOH
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-2-Carboxylic Acid, 6-Chloro-7-Fluoro- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.