Description

Bicyclo[2.2.1]Hept-5-Ene-2-Methanamine, n-Ethyl-, (1R,2S,4R)-Rel- (9Ci) is a high-purity, stereochemically defined chiral amine building block derived from norbornene. This compound matters for its unique structural rigidity and defined stereochemistry, which are critical for imparting specific spatial and electronic properties in advanced molecular synthesis. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as chiral ligand synthesis, catalyst development, and the creation of novel active ingredients.

Application

• Chiral Ligand and Catalyst Synthesis: Serves as a key precursor for constructing sophisticated ligands used in asymmetric catalysis, including hydrogenation and cross-coupling reactions.
• Pharmaceutical Intermediate: Utilized in the research and development of novel active pharmaceutical ingredients (APIs), where its rigid norbornene scaffold can influence bioavailability and receptor binding.
• Agrochemical Research: Employed in the synthesis of new crop protection agents, leveraging its structural properties to enhance efficacy and environmental profile.
• Material Science Monomer: Acts as a specialty monomer for developing polymers with unique thermal and mechanical properties due to the strained bicyclic structure.
• Organic Synthesis Building Block: Provides a versatile, stereodefined intermediate for complex natural product synthesis and methodological studies in academic and industrial R&D.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Methanamine, n-Ethyl-, (1R,2S,4R)-Rel- (9Ci)
CAS No.	259181-90-3
Molecular Formula	C10H17N
Molecular Weight	151.25 g/mol
Synonyms	rel-(1R,2S,4R)-N-Ethyl-2-(aminomethyl)norborn-5-ene; N-Ethyl-2-norbornene-2-methanamine (stereoisomer); 2-(Ethylaminomethyl)bicyclo[2.2.1]hept-5-ene; (1R,2S,4R)-N-Ethyl-2-(aminomethyl)bicyclo[2.2.1]hept-5-ene; Chiral N-Ethyl norbornenyl methanamine; Norbornene ethylamine derivative; Bicyclo[2.2.1]hept-5-ene-2-methanamine, N-ethyl-, (1R,2S,4R)-rel-
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hept-5-Ene-2-Methanamine, n-Ethyl-, (1R,2S,4R)-Rel- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the container in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; ensure the container is sealed under an inert atmosphere after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.