Description

3-Pyridinecarboxaldehyde-D4 is a deuterium-labeled isotopologue of 3-pyridinecarboxaldehyde (nicotinaldehyde), where four hydrogen atoms are replaced by deuterium. This compound is a critical stable isotope-labeled building block used in advanced research and development, particularly in the fields of analytical chemistry and pharmacology. It is primarily utilized by researchers and manufacturers in pharmaceutical development, agrochemical research, and analytical laboratories for use as an internal standard in mass spectrometry and for tracing metabolic pathways.

Application

• Pharmaceutical Research & Development: Serves as a deuterated intermediate in the synthesis of labeled drug candidates and metabolites for pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies.
• Analytical Chemistry: Employed as a high-purity internal standard in quantitative analysis via Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) to ensure accuracy and reliability.
• Metabolic Pathway Tracing: Used in mechanistic studies to investigate biochemical pathways and the fate of molecules in biological systems.
• Agrochemical Development: Acts as a key labeled precursor in the research and synthesis of novel, isotopically-labeled pesticides or herbicides.
• Material Science Research: Utilized in the development of specialty chemicals and advanced materials where isotopic labeling is required for study.

Basic Information

Product Name	3-Pyridinecarboxaldehyde-D4
CAS No.	258854-80-7
Molecular Formula	C6D4HNO
Molecular Weight	111.13 g/mol
Synonyms	Nicotinaldehyde-D4; 3-Formylpyridine-D4; Pyridine-3-carboxaldehyde-D4; Deuterated Nicotinaldehyde; (Pyridin-3-yl)methan-d-al-d3; 3-Pyridylcarboxaldehyde-D4; Isotopic Labeled 3-Pyridinecarboxaldehyde; Aldehyde-d4, 3-pyridinyl-
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxaldehyde-D4 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high isotopic purity. Each lot undergoes comprehensive analytical testing, including NMR (Nuclear Magnetic Resonance) and MS (Mass Spectrometry) to confirm chemical and isotopic purity. Certificates of Analysis (COA) detailing specific results for each parameter are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.