Description

2-Methoxytoluene-α,α,α-d3 is a deuterated isotopologue of 2-methoxytoluene (o-methylanisole), where the three hydrogen atoms on the methyl group attached to the aromatic ring are replaced with deuterium. This selective deuteration makes it a valuable non-radioactive isotopic tracer and an essential building block in advanced research and analytical chemistry. It is primarily utilized by scientists and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications such as mechanistic studies, metabolic pathway tracing, and as an internal standard in quantitative mass spectrometry.

Application

• Deuterated Internal Standard for the accurate quantification of 2-methoxytoluene and related compounds in complex matrices using GC-MS or LC-MS.
• Mechanistic Probe in organic chemistry and catalysis research to study reaction pathways, kinetic isotope effects (KIEs), and hydrogen/deuterium exchange processes.
• Precursor for Labeled Compounds in the synthesis of more complex deuterated molecules for pharmaceutical and agrochemical research and development.
• Metabolic Tracing in biological and environmental studies to track the fate and transformation of methoxytoluene derivatives.
• NMR Spectroscopy Solvent & Analyte, providing a unique spectroscopic signature free from proton signals at the labeled site.
• Material Science Research for investigating the properties of deuterated polymers or liquid crystals where isotopic purity affects physical characteristics.

Basic Information

Product Name	2-Methoxytoluene-α,α,α-d3
CAS No.	258832-47-2
Molecular Formula	C9H8D3O
Molecular Weight	138.20 g/mol
Synonyms	o-Methylanisole-d3; 1-Methoxy-2-(trideuteriomethyl)benzene; 2-(Trideuteriomethyl)anisole; Deuterated o-Methylanisole; 2-Methoxytoluene-d3; o-Methoxytoluene-α,α,α-d3; Anisole, o-methyl-d3; Benzene, 1-methoxy-2-(methyl-d3)-
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced and handled under strict quality protocols to ensure isotopic and chemical purity. Each batch of 2-Methoxytoluene-α,α,α-d3 is characterized by NMR, GC-MS, and IR spectroscopy to confirm structure, isotopic enrichment (typically >98 atom % D), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.