Description

7-Bromo-2-Methyl-1,2,3,4-Tetrahydroisoquinoline is a versatile and high-value brominated tetrahydroisoquinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a functionalized scaffold for constructing complex nitrogen-containing heterocycles, which are pivotal in pharmaceutical discovery and material science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, receptor modulators, and enzyme inhibitors.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the tetrahydroisoquinoline core.
• Organic Synthesis: Serves as a versatile precursor for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex substituents.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Precursor: Used in the research and development of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probe: Acts as a scaffold for developing molecular probes to study biological pathways and protein function.

Basic Information

Item	Details
Product Name	7-Bromo-2-Methyl-1,2,3,4-Tetrahydroisoquinoline
CAS No.	258515-54-7
Molecular Formula	C10H12BrN
Molecular Weight	226.11 g/mol
Synonyms	7-Bromo-2-methyl-1,2,3,4-tetrahydroisoquinoline; 2-Methyl-7-bromo-1,2,3,4-tetrahydroisoquinoline; 7-Bromo-2-methyl-3,4-dihydro-1H-isoquinoline; 1,2,3,4-Tetrahydro-7-bromo-2-methylisoquinoline; 258515-54-7; 7-Bromo-2-methyl-THIQ
EINECS	Contact for details

Quality Control

Our 7-Bromo-2-Methyl-1,2,3,4-Tetrahydroisoquinoline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring reliable batch-to-batch consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.