Description

4-Pyridinemethanol,3-Mercapto-(9Ci) is a specialized heterocyclic building block featuring both a hydroxymethyl and a thiol (mercapto) functional group on the pyridine ring. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients. The compound's reactivity allows for selective modifications, enabling the construction of targeted chemical libraries and potential drug candidates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in areas requiring metal-chelating or thiol-reactive pharmacophores.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides where the pyridine-thiol structure can impart specific biological activity.
• Ligand Synthesis: Serves as a precursor for creating chelating ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and material science.
• Bioconjugation Chemistry: The thiol group allows for use in linking strategies to proteins, peptides, or other biomolecules for probe or conjugate development.
• Material Science Precursor: Can be utilized in the synthesis of functionalized polymers or metal-organic frameworks (MOFs) with tailored surface properties.
• Chemical Biology Probes: Acts as a starting point for creating activity-based probes or inhibitors targeting cysteine proteases or other thiol-reactive enzymes.

Basic Information

Product Name	4-Pyridinemethanol,3-Mercapto-(9Ci)
CAS No.	258497-34-6
Molecular Formula	C6H7NOS
Molecular Weight	141.19 g/mol
Synonyms	3-Mercapto-4-(hydroxymethyl)pyridine; 4-(Hydroxymethyl)pyridine-3-thiol; 3-Mercapto-4-pyridinemethanol; 3-Mercapto-4-pyridylmethanol; (3-Mercaptopyridin-4-yl)methanol; 4-Pyridinemethanol, 3-mercapto-; 3-Mercapto-4-(hydroxymethyl)pyridine (9CI)
EINECS	Contact for details

Quality Control

Every batch of 4-Pyridinemethanol,3-Mercapto-(9Ci) is produced and tested under strict quality management protocols to ensure consistency and purity for research applications. Our standard grade typically meets a high purity specification suitable for synthetic chemistry. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing key parameters such as identity, purity, and impurity profile. We support custom synthesis and can tailor purity specifications to meet specific project requirements under cGMP guidelines if needed.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere to prevent oxidation of the thiol group. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.