Description

[4-(Dimethylamino)Phenyl](Diphenylphosphoryl)Methanol is a specialized organophosphorus compound featuring a tertiary amine and a phosphine oxide functional group. This unique structure makes it a valuable intermediate in advanced synthetic chemistry, particularly for constructing complex molecular architectures. It is primarily sought by research institutions and chemical manufacturers involved in pharmaceutical development, materials science, and the synthesis of novel ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring chiral phosphine ligands or specific amine-phosphorus motifs.
• Ligand Precursor in Catalysis: Serves as a precursor for the development of novel phosphine-oxazoline (PHOX) and related hybrid ligands used in asymmetric hydrogenation and cross-coupling reactions.
• Materials Science Research: Utilized in the development of organic electronic materials, such as charge-transport layers or as a functional monomer for specialty polymers.
• Agrochemical Synthesis: An intermediate in the research and production of advanced crop protection agents with specific activity profiles.
• Academic & Industrial R&D: Employed in methodological studies and the discovery of new chemical reactions due to its multifunctional reactivity.

Basic Information

Product Name	[4-(Dimethylamino)Phenyl](Diphenylphosphoryl)Methanol
CAS No.	258347-71-6
Molecular Formula	C21H22NO2P
Molecular Weight	351.38 g/mol
Synonyms	(4-Dimethylaminophenyl)diphenylphosphinylmethanol; α-Hydroxy-4-(dimethylamino)benzyldiphenylphosphine Oxide; [4-(Dimethylamino)phenyl](hydroxy)diphenylphosphorane; (Diphenylphosphoryl)(4-(dimethylamino)phenyl)methanol; N,N-Dimethyl-4-[(hydroxy)diphenylphosphorylmethyl]aniline
EINECS	Contact for details

Quality Control

Our production of [4-(Dimethylamino)Phenyl](Diphenylphosphoryl)Methanol adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by modern analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.