Description

(4-Phenyl-5-(Trifluoromethyl)Thiophen-2-Yl)Methanol is a high-value, multifunctional organic building block featuring a thiophene core substituted with phenyl and trifluoromethyl groups. This compound is prized for its unique electronic properties and structural versatility, making it a critical intermediate in advanced chemical synthesis. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for molecules targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Organic Electronic Materials: Acts as a precursor for conjugated molecules used in Organic Light-Emitting Diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) and introducing fluorine atoms into complex molecular architectures.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and scaled-up processes.

Basic Information

Item	Detail
Product Name	(4-Phenyl-5-(Trifluoromethyl)Thiophen-2-Yl)Methanol
CAS No.	256488-46-7
Molecular Formula	C12H9F3OS
Molecular Weight	258.26 g/mol
Synonyms	[2-(Hydroxymethyl)-5-(trifluoromethyl)-4-phenylthiophene]; 4-Phenyl-5-(trifluoromethyl)thiophene-2-methanol; 2-(Hydroxymethyl)-4-phenyl-5-(trifluoromethyl)thiophene; (4-Phenyl-5-trifluoromethyl-thiophen-2-yl)-methanol; α-(4-Phenyl-5-(trifluoromethyl)-2-thienyl)methanol
EINECS	Contact for details

Quality Control

Every batch of (4-Phenyl-5-(Trifluoromethyl)Thiophen-2-Yl)Methanol is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.