Description

5-Bromo-3-{Oxo[4-(Pyrimidin-2-Yl)Piperazin-1-Yl]Acetyl}-1H-Indole, 1-[(5-Bromo-1H-Indol-3-Yl)(Oxo)Acetyl]-4-(Pyrimidin-2-Yl)Piperazine is a high-purity, complex heterocyclic compound designed for advanced research and pharmaceutical development. This molecule is a critical intermediate for medicinal chemists exploring novel therapeutic agents, particularly in oncology and central nervous system (CNS) disorders. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors who require reliable, high-quality building blocks for drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for targets involving kinase or receptor modulation.
• Biochemical Probe Development: Utilized to create tool compounds for investigating biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Employed in university and institutional labs for cutting-edge chemical biology and drug discovery projects.

Basic Information

Item	Details
Product Name	5-Bromo-3-{Oxo[4-(Pyrimidin-2-Yl)Piperazin-1-Yl]Acetyl}-1H-Indole, 1-[(5-Bromo-1H-Indol-3-Yl)(Oxo)Acetyl]-4-(Pyrimidin-2-Yl)Piperazine
CAS No.	256417-42-2
Molecular Formula	C18H15BrN6O2
Molecular Weight	427.26 g/mol
Synonyms	5-Bromo-3-[oxo[4-(pyrimidin-2-yl)piperazin-1-yl]acetyl]-1H-indole; 1-[(5-Bromo-1H-indol-3-yl)(oxo)acetyl]-4-(pyrimidin-2-yl)piperazine; 5-Bromo-3-(2-oxo-2-(4-(pyrimidin-2-yl)piperazin-1-yl)acetyl)-1H-indole; 256417-42-2; 5-Bromo-3-(4-pyrimidin-2-ylpiperazine-1-carbonyl)-1H-indole (tautomeric form); 1-(5-Bromo-1H-indole-3-carbonyl)-4-(pyrimidin-2-yl)piperazine-2-one; 5-Bromoindole-3-glyoxylamide derivative
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-{Oxo[4-(Pyrimidin-2-Yl)Piperazin-1-Yl]Acetyl}-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.