Description

3-Phenyl-2-(Trifluoromethyl)Thiophene is a high-value, multi-functional heterocyclic building block characterized by its unique thiophene core substituted with phenyl and trifluoromethyl groups. This compound is prized for its ability to impart desirable electronic and steric properties to advanced materials and active pharmaceutical ingredients. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for use in organic synthesis, medicinal chemistry, and material science applications.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the synthesis of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Serves as a precursor for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene structure.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry: A valuable fluorinated building block for introducing the CF3 moiety into complex molecules, a common strategy in modern medicinal chemistry.
• Academic & Industrial R&D: Used extensively in exploratory chemistry for developing new synthetic methodologies and discovering compounds with novel properties.

Basic Information

Product Name	3-Phenyl-2-(Trifluoromethyl)Thiophene
CAS No.	256414-70-7
Molecular Formula	C11H7F3S
Molecular Weight	228.23 g/mol
Synonyms	2-(Trifluoromethyl)-3-phenylthiophene; 3-Phenyl-2-trifluoromethylthiophene; 2-Trifluoromethyl-3-phenylthiophene; Thiophene, 3-phenyl-2-(trifluoromethyl)-; 3-Phenyl-α,α,α-trifluoro-2-thiophenemethane
EINECS	Contact for details

Quality Control

Our production of 3-Phenyl-2-(Trifluoromethyl)Thiophene adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and industrial use. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to meeting the specific requirements of our global clientele, with quality systems designed to support cGMP and ISO standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.