Description

4-(Piperidin-4-Yl)Isoquinoline Dihydrochloride CAS NO 256372-14-2 is a high-purity, heterocyclic organic compound featuring a fused isoquinoline and piperidine structure. This advanced pharmaceutical intermediate is critical for medicinal chemistry research and the development of novel therapeutic agents targeting the central nervous system. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery programs for neurological and psychiatric disorders.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Neuroscience Drug Discovery: Serves as a core scaffold for developing ligands for sigma receptors, 5-HT receptors, or other CNS-related targets.
• Chemical Biology: Employed as a probe or tool compound for studying biological pathways and protein interactions.
• Preclinical Development: Supplied for in vitro and in vivo efficacy and safety testing of new therapeutic compounds.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	4-(Piperidin-4-Yl)Isoquinoline Dihydrochloride
CAS No.	256372-14-2
Molecular Formula	C₁₄H₁₈Cl₂N₂
Molecular Weight	285.21 g/mol
Synonyms	4-(4-Isoquinolinyl)-1-piperidine dihydrochloride; 4-(Isoquinolin-4-yl)piperidine dihydrochloride; 4-(Piperidin-4-yl)isoquinoline hydrochloride (1:2); 4-Piperidin-4-yl-isoquinoline dihydrochloride; 1-Piperidine, 4-(4-isoquinolinyl)-, dihydrochloride; Isoquinoline, 4-(4-piperidinyl)-, dihydrochloride
EINECS	Contact for details

Quality Control

Every batch of 4-(Piperidin-4-Yl)Isoquinoline Dihydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.