Description

4-(1-Piperazinyl)-1H-Indole Dihydrochloride is a high-purity, dihydrochloride salt derivative of a piperazinyl indole, a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the research and development of novel pharmacologically active molecules, particularly within the central nervous system (CNS) and oncology therapeutic areas. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in medicinal chemistry and the synthesis of complex bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates targeting serotonin and dopamine receptor systems.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Biochemical Tool Compound: Serves as a reference standard or ligand in receptor binding assays and other in vitro pharmacological studies.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct more complex, functionalized heterocyclic molecules.
• Academic Research: Utilized in university and institutional labs for exploratory research in organic chemistry and neuropharmacology.

Basic Information

Product Name	4-(1-Piperazinyl)-1H-Indole Dihydrochloride
CAS No.	255714-24-0
Molecular Formula	C12H16Cl2N4
Molecular Weight	287.19 g/mol
Synonyms	1H-Indole, 4-(1-piperazinyl)-, dihydrochloride; 4-Piperazin-1-yl-1H-indole dihydrochloride; 4-(Piperazin-1-yl)indole dihydrochloride; 4-Indolylpiperazine Dihydrochloride; 1-(1H-Indol-4-yl)piperazine Dihydrochloride; 4-(1-Piperazinyl)indole Dihydrochloride; 4-PIP dihydrochloride
EINECS	Contact for details

Quality Control

Our 4-(1-Piperazinyl)-1H-Indole Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.